An abandoned building, once a popular country saloon and dance hall, caught fire in Mission Valley Saturday.

A man hit and killed by a car in Lakeside in August has still not been identified, local medical officials said.

DUBAI, United Arab Emirates (AP) Israel launched airstrikes early Saturday targeting what it described as military targets in Iran in retaliation for a ballistic missile assault Oct. 1, officials said. There was no immediate information on damage in the Islamic Republic. Israel's military described the attack as precise strikes on military targets in Iran, ...

A couple Major League Baseball players with ties to San Diego will be suiting up for the Los Angeles Dodgers as they take on the New York Yankees in the World Series, which kicks off Friday afternoon.

Lesh was the oldest and one of the longest surviving members of the band that came to define the acid rock sound emanating from San Francisco in the 1960s.

A deadly outbreak of E. coli poisoning tied to McDonald's Quarter Pounders has expanded, with at least 75 people sick in 13 states, federal health officials said Friday.

Supervisor Terra Lawson-Remer renewed calls to designate the Tijuana River Valley as a federal superfund site on Thursday, days after the Board of Supervisors voted to delay initiate the process to participate in the program.

San Diego police arrested a suspect early Friday morning following a nearly five-hour standoff overnight in Carmel Valley, authorities said.

Staff at a Solana Beach shop are trying to get back to normal after thieves broke in and made off with some pricey specialized items.

Taylor Cram and her fiance Kurt Gairing have already set the date, booked their hotel room blocks, secured some of their vendors and picked out their 'perfect' wedding venue that checked all the boxes. The only issue is their wedding venue may no longer exist in a matter of weeks.

A man pleaded guilty to defrauding investors of millions through lies and deception, prosecutors said.